Origin of Life: Constructing the Building Blocks

Before you can assemble the large macro-molecules necessary for life you must have a ready supply of basic organic molecules. Imagine a primitive ocean. You need tons of sugars, amino acids, purines, pyrimidines, etc. There are a number of severe obstacles that must be overcome in getting a suitable ocean:
References:
Gish 1972
Gish 1984T
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